The end=' ' is just to say that you want a space after the end of the statement instead of a new line character. In Python 2.x you would have to do this by placing a comma at the end of the print statement. For example, when in a Python 3.x environment:
The end of support for .Net 4.8 is tied to the end of support of its parent OS. As Tanveer Badar wrote in his comment, the .Net 4.8 framework is included in Windows 11 (which was released a year after I wrote this comment, BTW) - so it's now tied to that OS.