The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.
BLAST (Basic Local Alignment Search Tool) is a tool that compares nucleotide or protein sequences to sequence databases. It is extensively used to identify sequence similarity and homology, thereby helping researchers infer the function and evolutionary relationships of sequences and identify the members of gene families.
BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families. There are several types of BLAST searches.
four different kinds of the BLAST program can be run: BLASTP, Protein Query Searching a Protein Database Each database sequence is compared to each query in a separate protein-protein pairwise comparison. BLASTX, Nucleotide Query Searching a Protein Database Each query is translated, and each of the six products is compared to
Standard Nucleotide BLAST BLASTN programs search nucleotide databases using a nucleotide query. more...
Enter a PHI pattern to start the search. PHI-BLAST may perform better than simple pattern searching because it filters out false positives (pattern matches that are probably random and not indicative of homology).
Smart Blast searches a protein query against the landmark database Enter Protein Query Sequence
Welcome to BLAST Help ¶ Getting started ¶ Web BLAST quick start guide New BLAST databases New Guide to BLAST home and search pages Blast report description Blast topics Frequently Asked Questions Getting Help ¶ Write to the help desk Mailing list BLAST tutorials About BLAST ¶ NCBI Handbook The Statistics of Sequence Similarity Scores BLAST ...