TCTMD: TCT 528: Sirolimus-Coated Balloon with Phospholipid Nanocarriers or Biodegradable Polymer Microspheres for Treatment of Coronary Artery Disease
TCT 528: Sirolimus-Coated Balloon with Phospholipid Nanocarriers or Biodegradable Polymer Microspheres for Treatment of Coronary Artery Disease
Phospholipids[1] are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids typically have omega-3 fatty acids EPA and DHA integrated as part of the phospholipid molecule. [2] .
phospholipid, any member of a large class of fatlike, phosphorus-containing substances that play important structural and metabolic roles in living cells.
Phospholipids are major components of the plasma membrane, the outermost layer of animal cells. Like fats, they are composed of fatty acid chains attached to a glycerol backbone. Unlike triglycerides, which have three fatty acids, phospholipids have two fatty acids that help form a diacylglycerol.
Phospholipids are essential molecules that play a key role in the structure and function of cellular membranes. Their amphipathic nature allows them to form bilayers, which serve as the foundational architecture for cell membranes, providing both structural integrity and functional versatility.
Phospholipids make up only about 2 percent of dietary lipids. They are partially water-soluble and partially fat-soluble and are found in both plants and animals. Phospholipids are crucial for building the protective barrier, or membrane, around your body’s cells.
Phospholipids are derivatives of glycerol-3-phosphate in which the glycerol backbone is attached to two fatty acids on one end and esterified phosphoric acid and an organic alcoholic group on the other.