EurekAlert!: Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and ...
MSN: RNA binding proteins found essential for regulatory T cell function and immune homeostasis
Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function of regulatory T cells in the immune system. As their name suggests, ...
RNA binding proteins found essential for regulatory T cell function and immune homeostasis
The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
EurekAlert!: U of T researchers discover DNA-binding C2H2 zinc finger proteins also regulate RNA processing
U of T researchers discover DNA-binding C2H2 zinc finger proteins also regulate RNA processing
Understanding gene regulation is critical to deciphering cellular function and disease mechanisms. Nuclear factors and RNA-binding proteins (RBPs) are key regulators that control gene expression at ...
Transcription factors are proteins that can bind to DNA and affect the expression of genes; some are known as master regulators that can have a wide impact and affect crucial processes like ...
EurekAlert!: How proteins bind to RNA: the dual mechanism of zinc fingers and disordered regions
RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from Institute of Science Tokyo, Japan. Using ...
How proteins bind to RNA: the dual mechanism of zinc fingers and disordered regions