In part 1, the initial model was selected and given a Trp residue for robust quantitation (along with 5 other mutations), generating the intermediate structure pdb:7KAE. In part 2, structure 7KAE was ...
Carbonic anhydrase inhibitors (CAIs) have long represented a versatile class of agents in clinical medicine. By targeting the zinc metalloenzymes responsible for rapidly converting carbon dioxide to ...
The New England Journal of Medicine: Clinical Experiences with a New Carbonic Anhydrase Inhibitor as an Oral Diuretic
Clinical Experiences with a New Carbonic Anhydrase Inhibitor as an Oral Diuretic
The New England Journal of Medicine: Blood Carbonic Anhydrase Activity and Zinc Concentration in Infants with Respiratory-Distress Syndrome
CARBONIC anhydrase is a zinc metalloenzyme that reversibly catalyzes the hydration of carbon dioxide to bicarbonate and hydrogen ions according to the following equation 1: Blood was obtained from ...
Blood Carbonic Anhydrase Activity and Zinc Concentration in Infants with Respiratory-Distress Syndrome